Cincinnati - Pittsburgh

Eight-Day / Seven-Night Cruise
Departing from Cincinnati, OH or Pittsburgh, PA

Experience the beauty, mystic, and fascinating lore of the Ohio River on American Cruise Lines’ brand new authentic paddlewheeler, Queen of the Mississippi. Relax on the greatest paddlewheeler to ever grace the Ohio River as you follow the routes of brave explorers who sought fame and fortune on the world’s first steamboats. While the churn of the paddlewheel blends with the sounds of the river, you’ll rediscover the America of the pioneers, the America of boundless optimism and unlimited possibilities. The Queen of the Mississippi will embody the spirit of traditional Mississippi River cruising and the grandeur of the riverboats of the past while offering all the modern comforts and amenities American Cruise Lines passengers have come to expect.

Request a Free Brochure or call 1-800-460-4518 for additional cruise details.

Cincinnati - Pittsburgh Cruise Map

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Day 1
Cincinnati, OH

Cincinnati SkylineAs you begin your journey aboard the Queen of the Mississippi, the first thing you will notice is the city of Cincinnati’s distinctive skyline rising up from the stately Ohio River. Beyond the beautiful landscape, however, this city boasts a rich history and cultural heritage and has struck a compelling balance between its storied past and resurgent present. This robust city is home to the world-class Cincinnati Zoo and Botanical Garden and the Cincinnati Museum Center.

Day 2
Maysville, KY

Maysville TrolleyHistory is abundant in Maysville, Kentucky. Experience the Freedom Trail by partaking in the Underground Railroad Tour or visiting the Harriet Beecher Stowe Slavery to Freedom Museum. Spend your time shopping in downtown Maysville or take in the museum, theater, and musical culture of Rosemary Clooney, whose singing career took her from small town Maysville, Kentucky to the spotlights of Hollywood. Her hits include White Christmas with Bing Crosby.

Day 3
Portsmouth, OH

Small town charm is abundant in Portsmouth, Ohio. Spend your time browsing Portsmouth’s Historic Boneyfiddle District and get lost in the nostalgia you will find in their antique and specialty shops. Learn about the history of Portsmouth depicted in the Floodwall Mural, one of the world’s largest mural projects. The Floodwall Mural is 20 feet high and extends for 2,200 feet along the Ohio River. Experience Portsmouth’s creative culture through its many museums, performing arts centers, and frequent outdoor exhibitions.

Day 4
Gallipolis, OH

Beautiful Home In Gallipolis, OHExperience the breathtaking views from your exquisite stateroom as the Queen of the Mississippi churns along the Ohio River to Gallipolis. This charming town began as a small French settlement of log cabins dating back to the 1790’s. The site of the original settlement is now City Park in the center of town, and is surrounded by antique shops right near our berth. Enjoy life on the farms when you visit Green Valley Farms, which was made famous for raising Grand Champion thoroughbreds.

Day 5
Point Pleasant, WV

Fort GuardThis area was explored by George Washington. His diary describes this land as a “pleasant point.” Now, you can explore through this pleasant little town by visiting the historic Fort Randolph and Krodel Park, the site of many battles during the Revolutionary War. Be sure to also visit Point Pleasant Museum and the location of the “First battle of the American Revolution.”

Day 6
Marietta, OH

Fountain GeyserRelax on a lounge chair aboard the Queen of the Mississippi as the paddlewheeler leisurely cruises along the Ohio River through the picturesque town of Marietta. Marietta has a wonderful shopping area filled with antique stores, galleries, confectionaries, and even a brewery. This town will charm you and its history will amaze you. Founded in 1788, Marietta was the first settlement in what was then the Northwest Territory. Be sure to visit the historic architecture, the Ohio River Museum, and the Fenton Art Glass Factory.

Day 7
Wheeling, WV

Wheeling WVNestled among the banks of the Ohio River, Wheeling began as a pre-revolutionary outpost, but with industrialization it became a hub of commerce on the Ohio River. Now, you can tour through the town’s impressive historic buildings, including the legendary Oglebay Mansion, and catch a glass blowing demonstration at the Carriage House Museum.

Day 8
Pittsburgh, PA

From our berth at Station Square, you will have the city at your finger tips. Ride the Pittsburgh inclines to the top of Mount Washington, where the view of the city and Ohio River is second to none. Visit the Heinz History Center, where several museums offer the fascinating history of Pittsburgh and the Ohio River Valley. As you disembark from your journey along the Ohio River, be sure to take one last glimpse at the America of the pioneers, the America of boundless optimism and unlimited possibilities.

Mississippi River Cruises on Queen of the Mississippi

Beneath the gleaming woodwork and brass fixtures aboard Queen of the Mississippi is a framework of modern cruise ship technology that provides passengers with the most comfortable vacation imaginable as we cruise the Mississippi and Ohio Rivers from New Orleans to Minneapolis or Cincinnati, OH.  The Queen of the Mississippi features the most spacious staterooms in the industry and provides more space per passenger than any other river cruise ship.Click play to see more.

Date # of Nights Cruise Departure Location Ship

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Queen of the Mississippi

Queen of the Mississippi delivers an experience unlike any other riverboat. Breathing life into a once dormant market, the paddlewheeler is the first built specially for the Mississippi River in nearly 20 years and was modeled after traditional Victorian-style riverboats of the late 1800s. Queen of the Mississippi offers all of the amenities and comforts expected by today’s travelers, including large staterooms with private balconies, hotel-style bathrooms, complimentary room service, WiFi, and much more. Transporting guests back in time in the most elegant fashion, the experience aboard Queen of the Mississippi is a seamless blend of old and new. Beneath her historic décor, gleaming woodwork and brass fixtures is a framework of modern cruise ship technology that provides passengers with the most comfortable and upscale vacation imaginable on America’s Rivers.  
Rate Schedule Per Person A AAR AAL AAC Owner's Suite Single w/ Balcony Single
7 Nights $4,195 $4,830 $5,350 $5,485 $6,885 $6,145 $5,580

Rates subject to change


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Take a virtual tour of Queen of the Mississippi, click here.