Upper Mississippi River Cruise

St. Louis, MO/Alton, IL to St. Paul, MN

St. Paul, MN to Alton, IL/ St. Louis, MO

9 Days / 8 Nights

Cruise Overview

A journey along the Upper Mississippi River is an enriching experience, embodying hometown Americana and the breathtaking scenery that has inspired the country’s most legendary writers, artists, and musicians. It was here that the great American writer Mark Twain used the majestic river and its scenic bluffs as the settings in his most popular works. In his book “Life on the Mississippi,” he described traveling on this part of the river as “always through enchanting scenery, there being no other kind on the Upper Mississippi.” Visit his boyhood home in Hannibal, where the characters of Huck Finn, Tom Sawyer, and Becky Thatcher come to life.

Explore the beautiful gardens and historic homes of the region in the company of our carefully selected expert guides. From your private balcony, admire stretches of undeveloped countryside, ornamented with pelicans, soaring eagles, and blue herons. Weave among hundreds of picturesque islands and through the amazing engineering of dams and navigation locks.  

Along the way, be treated to the gracious hospitality of our crew and savor an exquisite menu, featuring dishes masterfully prepared by our culinary team, with a dash of local flavor.  

Just as it was back in Mark Twain’s day, every riverboat on the Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary. The river has a mind of its own and our sailing schedules must adapt to it. This is part of the adventure and American Cruise Lines will always work to provide a seamless travel experience.   

Ask about our Current Savings and our Pre-Cruise Packages which include a premium hotel stay and transportation to the ship.

Upper Mississippi River Cruise Itinerary

Ships

Inaugurated 2015
Guest Capacity 150
Rooms 84
Common Areas 6
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American Heritage

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Inaugurated 2021
Guest Capacity 180
Rooms 91
Common Areas 6
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American Melody

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Inaugurated 2023
Guest Capacity 180
Rooms 91
Common Areas 6
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American Serenade

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Inaugurated 2022
Guest Capacity 180
Rooms 91
Common Areas 6
Ship Profile Deck 1 Highlighted Deck 2 Highlighted Deck 3 Highlighted Deck 4 Highlighted Deck 5 Highlighted

American Symphony

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Deck Plan 5

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Upcoming Cruises

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