Dates & Fares for Complete Mississippi River Cruise

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23 Days - 22 Nights One Way 22 Ports

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Map showing a Mississippi River cruise between New Orleans and St. Paul, visiting Oak Alley, Houmas House, Baton Rouge, St. Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cape Girardeau, St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, Red Wing, and Minneapolis
Start Date: May 23, 2025
Complete Mississippi River Cruise
From $15,890
ON SALEFrom $15,890 $14,890
SOLD OUT
  • American Melody | American Riverboat
  • 23 Days / 22 Nights | 22 Ports of Call
  • One Way from New Orleans, LA to St. Paul, MN
  • Complimentary Airfare Included
  • Complimentary Hotel Stay Included
More +
Questions? Contact a Dedicated Cruise Specialist
800-460-4518
Map showing a Mississippi River cruise between New Orleans and St. Paul, visiting Oak Alley, Houmas House, Baton Rouge, St. Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cape Girardeau, St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, Red Wing, and Minneapolis
Start Date: Jun 13, 2025
Complete Mississippi River Cruise
From $15,890
ON SALEFrom $15,890 $14,890
SOLD OUT
More +
Questions? Contact a Dedicated Cruise Specialist
800-460-4518
Map showing a Mississippi River cruise between New Orleans and St. Paul, visiting Oak Alley, Houmas House, Baton Rouge, St. Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cape Girardeau, St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, Red Wing, and Minneapolis
Start Date: May 22, 2026
Complete Mississippi River Cruise
From $15,890
ON SALEFrom $15,890 $0
SOLD OUT
  • American Melody | American Riverboat
  • 23 Days / 22 Nights | 22 Ports of Call
  • One Way from New Orleans, LA to St. Paul, MN
  • Complimentary Airfare Included
  • Complimentary Hotel Stay Included
More +
Questions? Contact a Dedicated Cruise Specialist
800-460-4518
Map showing a Mississippi River cruise between New Orleans and St. Paul, visiting Oak Alley, Houmas House, Baton Rouge, St. Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cape Girardeau, St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, Red Wing, and Minneapolis
Start Date: Jun 12, 2026
Complete Mississippi River Cruise
From $15,890
ON SALEFrom $15,890 $0
SOLD OUT
More +
Questions? Contact a Dedicated Cruise Specialist
800-460-4518
Map showing a Mississippi River cruise between New Orleans and St. Paul, visiting Oak Alley, Houmas House, Baton Rouge, St. Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cape Girardeau, St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, Red Wing, and Minneapolis
Start Date: May 21, 2027
Complete Mississippi River Cruise
From $15,890
ON SALEFrom $15,890 $0
SOLD OUT
  • American Melody | American Riverboat
  • 23 Days / 22 Nights | 22 Ports of Call
  • One Way from New Orleans, LA to St. Paul, MN
  • Complimentary Airfare Included
  • Complimentary Hotel Stay Included
More +
Questions? Contact a Dedicated Cruise Specialist
800-460-4518
Map showing a Mississippi River cruise between New Orleans and St. Paul, visiting Oak Alley, Houmas House, Baton Rouge, St. Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cape Girardeau, St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, Red Wing, and Minneapolis
Start Date: Jun 11, 2027
Complete Mississippi River Cruise
From $15,890
ON SALEFrom $15,890 $0
SOLD OUT
More +
Questions? Contact a Dedicated Cruise Specialist
800-460-4518
About American Riverboat | 180 Guests

The brand new American Riverboats have elevated the standard for riverboat cruising across the country. This new class of modern riverboats is the first of its kind in the U.S. and features contemporary styling, a grand multi-story atrium in the center of the ship, a variety of sizable lounges, and private balconies in each spacious stateroom.

What's included on our American Riverboats:

  • Inaugurated 2018-2023
  • Contemporary styling throughout
  • Multi-story glass atrium in center of the ship
  • Skywalk included on select ships (American Serenade, American Symphony, and American Melody)
  • Signature Sky Lounge with panoramic views
  • Expanded suites – the largest among our fleet
  • Private balconies on all staterooms
  • Sun deck
  • Outdoor cafĂ© dining option
  • Indoor fitness center

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