Cruise the most amazing destinations across the United States

Every destination has a story to tell. Explore our ports and discover a unique adventure waiting at every stop.

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Mississippi River Cruises

5 to 22 Days Itineraries

Mississippi River Cruises

Embark upon a once-in-a-lifetime Mississippi River adventure with American Cruise Lines. Choose from our nine amazing itineraries that sail the legendary Mississippi, Ohio, and Cumberland Rivers, with cruises running from New Orleans to the Twin Cities.

Columbia & Snake River Cruises

5 to 11 Day Itineraries

Columbia & Snake River Cruises

Follow the footsteps of the epic Lewis and Clark Expedition as you cruise the legendary Columbia and Snake Rivers. Aboard the newest riverboats in the region, you will be amazed by the beautiful and ever-changing landscapes, including the Columbia River Gorge, Multnomah Falls and Mount St. Helens.

New England Cruises

8 to 11 Day Itineraries

New England Cruises

The islands and harbors of New England and Maine are among the most desired summer vacation retreats. From the quaint island villages of Nantucket and Martha's Vineyard, to the rugged beauty of the Maine coast, we have created captivating small ship cruise itineraries for the most discerning traveler.

What sets us apart

Our Ships

Our Ships

The newest and most modern in America

Personalized Hospitality

Personalized Hospitality

Attentive and gracious service

World Class Cuisine

World Class Cuisine

Sourced by our master chefs

An American Experience

An American Experience

American-made, crew and destinations

Daily Onboard Entertainment

Daily Onboard Entertainment

Musicians, historians and naturalists

Spacious Accommodations

Spacious Accommodations

The largest staterooms of any cruise ship

Complimentary & Inclusive

Complimentary & Inclusive

Cocktails, pre-cruise stay, excursions

Private Balconies

Private Balconies

Unobstructed views, breathtaking scenery