Upper Mississippi River Cruise

St. Louis, MO to St. Paul, MN

St. Paul, MN to St. Louis, MO

8 Days / 7 Nights

Cruise Overview

The dramatic landscapes of the Upper Mississippi River have long inspired artists, writers, and steamboat passengers. It was here that literary great Mark Twain used the majestic river and its scenic bluffs as the settings in his most popular works. Visit his boyhood home in Hannibal, where the characters of Huck Finn, Tom Sawyer, and Becky Thatcher come to life.

Explore the beautiful gardens and historic homes of the region. Get close to nature in Red Wing as you witness a variety of bald eagle nests. Enjoy a guided tour of the Black Hawk State Historic Site which celebrates the story of the Sauk and Meskwaki Indians who once called Davenport home.

Just as it was in Mark Twain’s day, every cruise on the Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary. The river has a mind of its own and our sailing schedules must adapt to it. This is part of the adventure and American Cruise Lines will always work to provide a seamless travel experience.   

Ask about our Current Savings and our Complimentary Pre-cruise Packages which include a premium hotel stay and transportation to the ship.

Upper Mississippi River Cruise Itinerary


Inaugurated 2015
Guest Capacity 150
Rooms 84
Common Areas 6
Inaugurated 2021
Guest Capacity 175
Rooms 91
Common Areas 6
Inaugurated 2016
Guest Capacity 185
Rooms 98
Common Areas 6
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Dates & Fares

Upper Mississippi River Cruise

8 Days - 7 Nights One Way 8 Ports of Call

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