Complete Mississippi River Cruise Relax and enjoy the passing landscapes as we make our way along the Mississippi River from New... Learn more
Cumberland River Cruise Cruise from Nashville to St. Louis, following the Cumberland and Mississippi Rivers on a route of... Learn more
Grand Heartland Cruise Enjoy an epic 15-day journey on our Grand Heartland Cruise. This cruise on the Mississippi River... Learn more
Highlights of the Mississippi River Your roundtrip Mississippi River adventure begins and ends in New Orleans, a melting pot of French, ... Learn more
Lower Mississippi River Cruise Traveling the Lower Mississippi with American Cruise Lines is an experience like no other.... Learn more
Mississippi River Gateway Cruise Cruise the Mississippi River from the banks of the Bayou to the shores of St. Louis. Your... Learn more
New Orleans - New Orleans Board one of our brand new riverboats, as we celebrate the music, history, and culture of the Lower ... Learn more
Ohio River Cruise Experience the picturesque waterways of the Mississippi and Ohio Rivers on this 11-day adventure.... Learn more
Upper Mississippi River Cruise The dramatic landscapes of the Upper Mississippi River have long inspired artists, writers, and... Learn more
Grand New England Cruise Discover the majestic seafaring heritage of coastal towns and quaint island villages on the... Learn more
Hudson River Cruises Surrounded by the Catskill Mountains on the western shore and the Taconic and Berkshire Hills to... Learn more
Maine Coast and Harbors Cruise People have been drawn to the spectacular coast of Maine throughout history. As your small ship... Learn more
New England Fall Foliage Experience the breathtaking beauty of the East Coast on this brand new 8-day itinerary. From Boston ... Learn more
New England Islands Cruise Travel with American Cruise Lines as we discover the New England Islands. Each day is filled with... Learn more
Alaska Inside Passage Cruise Discover the majestic splendor of a summer in Alaska on an incredible 15-day journey. Cruise the... Learn more
Columbia and Snake Rivers Cruise Embrace your inner pioneer as you travel along the epic route forged by Lewis and Clark more than... Learn more
Grand Puget Sound Your magnificent voyage begins in the seaport city of Seattle, harbor hopping through the Puget... Learn more
Highlights of the Columbia River Our brand new Highlights of the Columbia River cruise offers the best of the Pacific Northwest and, ... Learn more
Northwest Pioneers Cruise Experience the historic journey of the intrepid explorers Lewis and Clark, while admiring the... Learn more
Puget Sound and San Juan Islands Cruise Travel to where the Cascade and Olympic Mountains meet the sea, forming the stunning Puget Sound... Learn more
Southeast Alaska Cruise Experience the breathtaking scenery of Alaska in the sophisticated atmosphere of the region’s most... Learn more
American Revolution Cruise Travel back to the dawn of America, on our brand new 11-day American Revolution cruise. Explore the ... Learn more
Chesapeake Bay Cruise The Chesapeake Bay is alive with history and culture. From the vibrant harbor of Baltimore, you... Learn more
East Coast Autumn Cruise Cruising the East Coast in autumn is a delight for the senses. This unique itinerary begins in New... Learn more
East Coast Inland Passage Cruise Cruise the East Coast Inland Passage through a rich past that has influenced our country since the... Learn more
Grand Historic South Cruise There is no destination that compares to the natural beauty found along the scenic Intracoastal... Learn more
Great Rivers of Florida Cruise On this epic cruise, sail a route that adventurous passengers first followed in the 19th Century in ... Learn more
Historic South and Golden Isles Cruise The Intracoastal Waterway, home to some of the most beautiful historic cities in America, is a... Learn more
Mark Twain Cruise Few American authors are as beloved as Samuel Clemens, better known by his pen name, Mark Twain.... Learn More
New Orleans Civil War Cruise Delve deep into the history of the Civil War on this special theme cruise which explores... Learn More
Lewis & Clark Cruise Two hundred years ago, Lewis & Clark set out on their pioneering journey into the West. Follow... Learn More
Crabfest Cruise Cruise the scenic Chesapeake Bay and delight your palate with fresh seafood from the "Blue Crab... Learn More
Grand New England Lobsterbake Cruise Mention New England and one of the first things that comes to mind is lobster. Enjoy a traditional Learn More
Food & Wine Cruise The Pacific Northwest is known for its delicious seafood and delectable wines. Savor exquisite... Learn More
Music Cruise Delight in the sounds of Jazz and Blues that fill the air as we cruise the Mississippi River and... Learn More
Culinary Cruise The Culinary Cruise along the Lower Mississippi River cruise is perfect for food lovers who relish... Learn More
Tulip Festival Cruise Springtime in the Pacific Northwest is a wonderful time with one of the most magnificent... Learn More
Nashville Country & Blues Cruise Blues and Country music are distinctly American and both have deep roots on the banks of the... Learn More
Puget Sound Fall Foliage Experience brilliant fall foliage with American Cruise Lines' Fall Cruises as we cruise the Puget... Learn More
Hudson River Fall Foliage Experience brilliant fall foliage with American Cruise Lines' Fall Cruises as we cruise the Hudson... Learn More
Thanksgiving Cruise Celebrate Thanksgiving with American Cruise Lines. This year we invite you to join us as we cruise... Learn More
Christmas Cruise Join us for a joyful celebration aboard our Christmas Cruise. Enjoy cruising the Mississippi River... Learn More
New Years Cruise Let American Cruise Lines help you ring in the New Year as we travel round trip from New Orleans.... Learn More