Find a Southeast US Cruise

European explorers found sanctuary in the bountiful lands of the Southeast centuries ago. Now these tranquil waterways allow American Cruise Lines to provide guests with an exploration of history and natural beauty. Discover Southern charm as we cruise the Intracoastal Waterway or the early American ideal on our Chesapeake Bay Cruise.

Historic South and Golden Isles Cruise

Charleston, SC to Amelia Island, FL

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8 Days / 7 Nights

On this Golden Isles river cruise from Charleston to Amelia Island you'll see the extravagant homes of Jekyll Island, stroll through the cobblestone streets of Savannah, GA, and discover dolphins on Hilton Head Island.

American Revolution Cruise

Baltimore, MD to Baltimore, MD

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11 Days / 10 Nights

History buffs will revel in this 11-day Baltimore round trip cruise. Guests explore the cities and towns that shaped our country, including Washington D.C., Colonial Williamsburg, and Jamestown.

Great Rivers of Florida Cruise

Jacksonville, FL to Jacksonville, FL

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8 Days / 7 Nights

This Florida 8-day Amelia Island round trip cruise features fascinating stops such as Green Cove Springs, St. Augustine, and Palatka.

Chesapeake Bay Cruise

Baltimore, MD to Baltimore, MD

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8 Days / 7 Nights

This 7-day riverboat cruise takes guests to the "Crab Capital of the World", visits the U.S. Naval Academy in Annapolis as well as many of the other historic ports that define our Chesapeake Bay cruises.

East Coast Inland Passage Cruise

Baltimore, MD to Amelia Island, FL

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15 Days / 14 Nights

Guests will rediscover the east coast on this captivating Baltimore, MD, to Amelia Island, FL cruise. From Kitty Hawk, NC, where the Wright Brothers took flight, to Charleston, SC, Hilton Head, SC, and St. Simons Island, GA - guests will revel in the charm of the Southeast.

What sets us apart

Our Ships

Our Ships

The newest and most modern in America

Personalized Hospitality

Personalized Hospitality

Attentive and gracious service

World Class Cuisine

World Class Cuisine

Sourced by our master chefs

An American Experience

An American Experience

American-made, crew and destinations

Onboard Entertainment

Daily Onboard Entertainment

Musicians, historians and naturalists

Spacious Accommodations

Spacious Accommodations

Spacious Accommodations

Complimentary and Inclusive

Complimentary & Inclusive

Cocktails, pre-cruise stay, excursions

Private Balconies

Private Balconies

Unobstructed views, breathtaking scenery