Mississippi River Cruises

Cruising the Mississippi River and its tributaries is an exploration of the American spirit. Gliding past the rolling farmland on our paddlewheel riverboats American Heritage and American Splendor, is an experience set in a time past and a testament to the ingenuity of the pioneers who first traveled these waters.  The fabric of the region is brought to life through our delicious regional cuisine, great onboard music, and customized excursions to historic landmarks.  Enjoy one of our themed Mississippi River cruises, perfect for music aficionados, culinary connoisseurs and history enthusiasts.

What are Mississippi River Cruises?

Upper Mississippi River Cruises sail the area between St. Louis, Missouri and St. Paul, Minnesota.  Lower Mississippi River Cruises sail from Memphis, Tennessee and New Orleans, Louisiana. In addition to cruises directly on the Mississippi River, there are also cruises that explore its tributaries including the Ohio and Tennessee Rivers.

American Melody, an American Riverboat small cruise ship gliding along the Mississippi River, surrounded by lush greenery on the nearby shore.

Historic Mississippi River Cruise

New Orleans, LA to New Orleans, LA

Free Airfare* Plus Save up to $800
8 Days / 7 Nights
From
Original Price $3,630
Discounted Price$3,230
Reserve Now View Cruise Details
A historic plantation in Louisiana, Oak Alley Plantation, has two story pillars on all sides, grand porches, and is set amongst beautiful grounds and gardens with a red brick pathway with large oak trees on each side leading to the front door.

Lower Mississippi River Cruise

Memphis, TN to New Orleans, LA

Free Airfare* Plus Save up to $1,000
9 Days / 8 Nights
From
Original Price $4,295
Discounted Price$3,795
Reserve Now View Cruise Details
A distinguished older man impersonating Mark Twain with white hair and a white mustache, wearing a white suit and bow tie, showcasing a refined and classy appearance.

Upper Mississippi River Cruise

St. Louis, MO to St. Paul, MN

Free Airfare* Plus Save up to $1,200
9 Days / 8 Nights
From
$4,610
Reserve Now View Cruise Details
A live concert at the Grand Ole Opry in Nashville, where a male singer and his band performs in front of a large crowd of hundreds of people.

Music Cities Cruise

Memphis, TN to Nashville, TN

9 Days / 8 Nights
From
$4,295
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A large black cannon in the middle of Shiloh National Military Park in Savannah, with large trees and an American flag on a tall flag pole in the distance.

Tennessee Rivers Cruise

Chattanooga, TN to Nashville, TN

Free Airfare* Plus Save up to $1,500
9 Days / 8 Nights
From
Original Price $4,295
Discounted Price$3,545
Reserve Now View Cruise Details
A historic plantation in Louisiana, Houmas House Plantation has two story pillars on all sides, grand porches and is set amongst beautiful grounds and gardens. There are pink, purple, and orange colored flowers in the foreground, and a small pond along the right side of the land.

Mississippi Explorer Cruise

New Orleans, LA to Memphis, TN

Free Airfare* Plus Save up to $1,500
12 Days / 11 Nights
From
$6,360
Reserve Now View Cruise Details
A red cable car descends a forest hill overlooking the Ohio River and a Pittsburgh cityscape featuring a brideg with a yellow truss in the middle and several skyscrapers under a partly cloudy sky.

Ohio River Cruise

Louisville, KY to Pittsburgh, PA

Free Airfare* Plus Save up to $2,000
9 Days / 8 Nights
From
Original Price $4,610
Discounted Price$3,610
Reserve Now View Cruise Details
A view of the Great Smoky Mountains and the flatland below with several trees, accompanied by a bright yet cloudy sky. In the top left corner, there is a text overlay on a blue box that reads "Land & Cruise Package".

Great Smoky Mountains National Park

Knoxville, TN to Nashville, TN

12 Days / 11 Nights
From
$6,795
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The historic St. Francisville landmark the Rosedown, a yellow house with bright green shutters and two-story white pillars with a brick pathway surrounded by perfectly trimmed bushes and large trees leading to the red door.

Complete Mississippi River Cruise

New Orleans, LA to St. Paul, MN

Free Airfare* Plus Save up to $2,000
23 Days / 22 Nights
From
Original Price $15,890
Discounted Price$14,890
Reserve Now View Cruise Details
A man with a camera photographs a brick path at Oak Alley Plantation, with countless large trees perfectly in line on each side from a balcony.

Grand Heartland Cruise

St. Paul, MN to New Orleans, LA

Free Airfare*
16 Days / 15 Nights
From
$11,030
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American Heritage, an American Cruise Lines Paddlewheeler decorated with patriotic red white and blue bunting flags on the front railings, docked along the Mississippi River in Paducah, KY letting passengers off from the front of the ship.

Mississippi River Gateway Cruise

New Orleans, LA to Louisville, KY

12 Days / 11 Nights
From
$6,360
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Multiple tables and chairs line the blue American Riverboat deck floor with the view of the St. Louis Gateway Arch and several skyscrapers in the background.

Grand Ohio River Cruise

Pittsburgh, PA to St. Louis, MO

Free Airfare* Plus Save up to $1,600
16 Days / 15 Nights
From
Original Price $8,075
Discounted Price$7,275
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What sets us apart

Our Small Cruise Ships Our Small Cruise Ships

The newest and most modern in America

Personalized Service Personalized Service

Attentive and gracious service

World Class Cuisine World Class Cuisine

Customized by our master chefs

All-Inclusive All-Inclusive

All meals & snacks, cocktails & beverages, enrichment & excursions, tips & fees

Spacious Staterooms Spacious Staterooms

Largest staterooms in the industry

Private Balconies Private Balconies

Unobstructed views, breathtaking scenery

Onboard Enrichment Onboard Enrichment

Musicians, historians and naturalists

An American Experience An American Experience

American-made, crew and destinations