Mississippi River Gateway Cruise

Cruise the Mississippi River from the banks of the Bayou to the shores of St. Louis. Your journey starts in the French Quarter, the oldest neighborhood in the vibrant city of New Orleans, brimming with art, music, and culture.

Continue to Baton Rouge and Natchez, where you will experience the best in southern hospitality while touring historic homes and grand plantations. Enjoy a captivating lecture from our onboard Civil War historian on an exclusive tour of the Vicksburg National Military Park. While in Memphis, visit the famous Sun Studios, known as the birthplace of Rock n’ Roll.

Explore Paducah also known as “Quilt City,” and peruse its many museums and art galleries, before docking at St. Louis, home of The Gateway Arch, our nation’s tallest man-made monument.

Ask about our Current Savings and our Complimentary Pre-cruise Packages which include a premium hotel stay and transportation to the ship. Click the Schedules & Rates tab for details.

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Cruise Itinerary

Day
Ports of Call
1
New Orleans, LA
2
Baton Rouge, LA
3
Natchez, MS
4
Vicksburg, MS
5
Day of River Cruising
6
Memphis, TN
7
New Madrid, MO
8
Paducah, KY
9
Day of River Cruising
10
St. Louis, MO
11
St. Louis, MO

Mississippi River Gateway Cruise

Mississippi River Gateway Cruise

Explore America's heartland on this unprecedented journey. From New Orleans to St. Louis, cruise in modern comfort aboard one of the finest riverboats on the Mississippi. Enjoy spirited onboard entertainment and enrichment programs from regional experts who will turn each guided shore excursion into a fun and informative outing.

Ports of Call

  • New Orleans, LA
  • New Orleans, LA
  • Baton Rouge, LA
  • Natchez, MS
  • Vicksburg, MS
  • Memphis, TN
  • New Madrid, MO
  • Paducah, KY
  • St. Louis, MO
  • St. Louis, MO
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Day by Day

Reverse itineraries available. Please contact your Cruise Specialist for your specific Day By Day agenda.

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Pre-Cruise
New Orleans, LA

Each Mississippi itinerary comes complete with a Complimentary Pre-Cruise Package, providing you with a seamless way to board the ship and explore the local area. Arrive the day before your scheduled cruise date and American Cruise Lines will handle the rest. The package includes a premium hotel stay, where you can enjoy the city at your leisure. On the morning of the cruise, meet in the hotel lobby after breakfast and we will transport you to the ship to begin your cruise. All luggage will be brought directly from the hotel and placed in your stateroom aboard the ship.

*Pre-Cruise Package is not available for reservations made within 30 days of cruise date.

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Day  1
New Orleans, LA

Explore the French Quarter, with its architectural blend of Spanish, French, Creole, and American styles. Also known as the Vieux Carré, it is the oldest neighborhood in the city of New Orleans. The distinctive and romantic character of the area has long inspired writers and artists since the time of Mark Twain, Lafcadio Hern, and John James Audubon.

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Day  2
Baton Rouge, LA

Experience the wonder of Baton Rouge, Louisiana's capital, and one of the most historic and unforgettable cities in the South. Known as the Red Stick, Baton Rouge has everything you would expect to find in a state capital, but with a down-home flavor that is part of its charm. 

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Rosedown Plantation Tour - Complimentary Excursion

The affluent ambiance of the Rosedown Plantation is evident the minute you step on the property. As you walk down the flowered path lined with towering oaks towards the Main House, you will be greeted by our lively resident expert, Tammie Miller. On the tour, Tammie delves deep into the family history of Daniel and Martha Turnbull and how their experiences helped shape the Main House into a home. At the conclusion of your tour, time is set aside to explore the grounds on your own or relax in a rocking chair on the front porch with cold refreshments and some of Tammie’s freshly made cookies.

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USS Kidd

Known as the “Pirate of the Pacific,” this Fletcher-class destroyer is a memorial to the men and women that served in the American armed forces. Step back in time on this amazing tour as you witness original artifacts and aircraft from World War II.

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Historic Baton Rouge Tour - Complimentary Excursion

The vibrant history of Louisiana is evident throughout the state’s capital. After breakfast, you will be greeted at the ship by Philippa Blair and her visitor center representatives as they welcome you to Baton Rouge with vibrant Mardi Gras beads. Your first stop is the Louisiana Old State Capitol where you will experience a one-of-a-kind interactive film, made with the help of Disney, bringing you face-to-face with the ghost of the castle, Sarah Morgan. Afterward, Baton Rouge native, Ira Bobin, will serve as our tour guide and will bring you to the Louisiana State Museum, a completely interactive museum with three floors of displays detailing each region of Louisiana.

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Day  3
Natchez, MS

Perched on a bluff above the Mississippi River, Natchez is a city 300 years in the making. Over a thousand of its buildings are listed on the National Register of Historic Places. Upon closer inspection, you will soon discover that Natchez, while indeed a reflection of the past, is also alive in the present, filled with art, music, culture, and commerce.

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J.N. Stone House Tour & Concert

Upon arrival, you will be greeted by the fourth-generation owner, Joseph Stone, whose family has owned the home for over 135 years. Mr. Stone will guide you on a personal tour of his unique antebellum-style home and explain the many different purposes it has served over the years. Here, you can explore his eclectic collection of period-specific artwork and one-of-a-kind antiques. The afternoon concludes in the music hall with refreshments, as Mr. Stone performs an exclusive classical piano concert.

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Historic Longwood Exploration - Complimentary Excursion

Longwood is just one of the elegant historic houses that graces the historic district of Natchez. This octagonal house epitomizes the rise and fall of the South. As the Civil War began, the workmen stopped construction and the house was never completed. View the finished first floor with original family furnishings and the upper five stories that are still a work in progress. 

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Frogmore Plantation Tour

Our onboard experts tell many stories about southern life on a plantation; today you will learn about what life was really like. Our insightful local guide will accompany you from the ship to the cotton gin and will be your escort as you explore the 1,800-acre cotton plantation. In intimate groups, the plantation owners Lynette and Buddy Tanner will delve into plantation life, including the housing, music, and relationships between the owners and workers. You will have the opportunity to pick cotton directly from the field, participate in a live gospel performance, and witness the progress in cotton technology from Eli Whitney’s original gin to their modern 900 bales-per-day computerized plantation.

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Natchez Shuttle - Complimentary Excursion

Take a complimentary shuttle into the charming city of Natchez, MS. Explore this beautiful city’s shopping, museums, and other offerings at your own leisure before departing this popular destination.

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Day  4
Vicksburg, MS

U.S. history is alive in Vicksburg. This “Queen City of the Bluff” offers plenty of opportunities to take a step back in time. Civil War battlefields, century old churches, cotton fields, and restored train depots are just a few of the many intriguing landmarks that await your visit. Marvel in the beautiful antebellum-style homes and learn about  Vicksburg’s rich history as displayed on the riverfront murals.

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Vicksburg National Military Park - Complimentary Excursion

The night before our visit, our onboard Civil War historian gives a captivating lecture detailing all you are about to witness at Vicksburg National Military Park. After a hearty southern-inspired breakfast, you will be greeted by our private tour guide who will stay with you throughout the day to answer questions and provide additional information. Upon arrival at the park, rangers who are well-versed in Civil War history guide you on a customized tour that’s specific to the interests of the group. Your guides will take you through the restored ironclad gunboat, U.S.S Cairo, the battlefield where the Siege of Vicksburg took place, and the over 1,300 monuments dedicated to the brave souls who lost their lives.

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Day  5
Day of River Cruising

As we make our way from historic New Orleans to St. Louis, revel in the sights and sounds of the spectacular Mississippi River. Spend time chatting with other passengers in the lounges or enjoy a cocktail on your private balcony.

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Day  6
Memphis, TN

The largest city in Tennessee offers plenty to see, including Graceland, the W.C. Handy Museum; Shelby Farms, the largest urban park in the country; and the “twisted” Ornamental Metal Museum. In the heart of “Blues City,” you will find the Peabody Memphis, one of the city’s most popular attractions.

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Memphis City Experience - Complimentary Excursion

Relax and let your guide show you the highlights of this fascinating City on the Bluff. Memphis is located on the Mississippi River at the northern end of the Mississippi Delta where the Blues were born. Its history is linked to cotton and music. Visit the St. Judes Children's Research Hospital and the famous ducks of the Peabody Hotel. Drive by the iconic National Civil Rights Museum, the site where Dr. Martin Luther King, Jr. was assassinated; and Sun Studios, where many legendary recording artists got their start. As you explore the city, listen to the musical notes of up-and-coming artists on Beale Street.

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Deluxe Graceland Signature Tour

No trip to Memphis is complete without a trip to the home of the “King of Rock n’ Roll,” Elvis Presley.   Before venturing just outside of the city to Graceland, our knowledgeable guide takes you on a brief tour of the historic downtown and riverfront area.  American Cruise Lines offers the most in-depth experience available at Graceland, allowing you to explore fascinating exhibits such as Elvis’ museum, estate grounds, the jungle and trophy rooms, his gravesite, and much more.

* This is a Signature Shore Tour. Please call (800) 460-4518 for more information. 

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Day  7
New Madrid, MO

Originally founded in 1776 by Spanish Governor Esteban Rodriguez, early settlers of New Madrid were required to become citizens of Spain in order to reside here. Today, New Madrid is a living monument to early American history with sites including the Kochtitsky Home, the Trail of Tears, and Veterans Park.

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Historic Hayride

Ride through the quaint town of New Madrid on a beautiful hayride pulled by John Deere Tractor. Begin on the picturesque, newly completed River Walk, continuing on to the Historical Museum.

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Day  8
Paducah, KY

From quilting and shopping to learning about Civil War history, there is plenty to do in Paducah. Led by our expert guide, tour the city with a stop National Quilt Museum. You may also take tours retracing the town's tumultuous Civil War history.

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Paducah City Tour & National Quilt Museum

Let our local guide take you through the quaint city of Paducah. This tour has been carefully divided into three distinct sections to make sure you experience all that Paducah has to offer. First, tour the downtown as our local expert guide points out the areas’ many historical sites. Then, take a leisurely stroll along the riverfront where you will witness more than 50 life-sized panoramic murals depicting elements of Paducah’s past. End the tour at the National Quilt Museum, the world's largest museum devoted to quilt and fiber art.

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River Discovery Center - Complimentary Excursion

Just a short distance from the ship’s docking location is the River Discovery Center, where guests learn about the Four Rivers region. Explore state-of-the-art interactive exhibits such as the working lock and dam model and the pilothouse simulator which allows you test your skills and captain your own riverboat!

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Day  9
Day of River Cruising

Sit back and enjoy the gentle sounds of the paddlewheel as it churns the placid waters of the Ohio River. One of the highlights of this cruise is the chance to watch the ever-changing scenery as it passes by and experience the river as early explorers did centuries ago.

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Day  10
St. Louis, MO

St. Louis is known as the “Gateway to the West." Admire the scenic riverfront, highlighted by the majestic Gateway Arch, the largest man-made monument in the U.S. Enjoy St. Louis’ many world-class attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum.

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Discover St. Louis Tour - Complimentary Excursion

Enjoy a narrated tour of downtown St. Louis, the riverfront, Citygarden, and the historic neighborhoods of Soulard and Lafayette Square. Delight in a visit to St. Louis' 1,371 acre Forest Park, known as a natural oasis in an urban environment.

*Note: This tour is only offered on cruises ending in St. Louis, MO.

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Missouri History Musem

Enjoy a guided tour through two of the museum’s most popular exhibits; The 1904 World’s Fair: Looking Back at Looking Forward, an event that attracted over 200,000 visitors to the opening day and Route 66: Main Street through St. Louis, a roadway which played an important role in American History, not only in fact but in myth. Learn about the companies and tourist traps that travelers had to pass through.

*Note: This tour is only offered on cruises ending in St. Louis, MO.

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Day  11
St. Louis, MO

Departure day. End your day by relaxing at the Missouri Botanical Garden, one of the world’s most popular public gardens.

Experiences

On this 11- day journey from New Orleans to St. Louis, discover what makes the Mississippi River legendary. The delectable cuisine, the stunning scenery, and the fascinating historic landmarks is an experience for the soul.

Your Cruise Includes

Queen of the Mississippi

Built in 2015, Queen of the Mississippi offers an authentic paddlewheeler experience with all the comforts of home. Guests can enjoy large staterooms with private balconies, hotel-style bathrooms, complimentary room service, WiFi, and more. Experience breathtaking scenery from the privacy of your stateroom as the Queen of the Mississippi makes its way down the legendary river. 


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Owner's Suite

Deckplan

At a generous up to 445 sq. ft., the Owner’s Suites of Queen of the Mississippi offer the finest accommodations with unsurpassed views of the Mississippi River. With a spacious seating area and full-size bathrooms, each suite is a private sanctuary where you can unwind after a day of exploration in the tasteful comfort of your surroundings. Each of these suites features large sliding glass doors leading out to a private balcony, where you can enjoy the ever-changing scenery. Every modern amenity is at your fingertips, along with a desk, and spacious seating area.

AAM (Private Balcony)

Deckplan

Located on the top deck, these spacious staterooms feature scenic views of the passing landscape. At 328 sq. ft., you will enjoy all of the modern comforts that are expected of a premium hotel. These staterooms also offer full-size bathrooms and a walk-out private balcony where the grandness of the Mississippi can be appreciated.

AAC (Private Balcony)

Deckplan

Our AAC staterooms are conveniently located on the fourth deck and at 304 sq. ft. offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape. 

AAL (Private Balcony)

Deckplan

AAL staterooms can be found on the third deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with plush seating, a full-size bathroom, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. 

AAR (Private Balcony)

Deckplan

AAR staterooms can be found on the second deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with a full-size bathroom and a large private balcony with sliding glass doors.  

A

Deckplan

These 290 sq ft staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, all are equipped with modern amenities, full-size bathrooms, and closet space.

Single (Private Balcony)

Deckplan

Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

Single

Deckplan

A comfortable getaway, our Single staterooms offer individuals a spacious room with convenient amenities. At 203 sq. ft., all have interior entrances and large viewing windows where the sights of the Mississippi can be enjoyed.

Queen of the Mississippi Deck Plan

Deck

America

Launched in 2016, America is one of the finest Mississippi paddlewheelers ever built, introducing features never before seen on the Mississippi.  America embodies a casual ambiance and relaxed atmosphere while providing panoramic views of the passing scenery. With only 185 guests, fellow guests will quickly become new friends. 


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Owner's Suite (Private Balcony)

Deckplan

Each Owner’s Suite on America offers the finest accommodations on the Mississippi River with unsurpassed views of the passing scenery. A spectacular up to 445 sq. ft. of space is your private sanctuary to spread out and make yourself at home. Floor-to-ceiling sliding glass doors lead to an expansive private balcony offering private panoramic views throughout the room. Every modern amenity is at your fingertips, along with a spacious seating area, desk, and full-size bathroom.

AAM (Private Balcony)

Deckplan

Located on the top deck, these spacious staterooms feature commanding views of the passing Mississippi landscape. At 328 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor- to-ceiling sliding glass doors with a private balcony to offer panoramic views of the Mississippi from every angle.  These staterooms also offer a sitting area, desk, and full-size bathrooms and are the epitome of comfort and relaxation.

AAC (Private Balcony)

Deckplan

AAC staterooms are conveniently located on the fourth deck and at 304 sq.ft offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape.

AAL (Private Balcony)

Deckplan

AAL staterooms can be found on the third deck of America. Enjoy a luxurious 304 sq. ft. of living space that is equipped with plush seating, full-size bathrooms, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. 

AAR (Private Balcony)

Deckplan

AAR staterooms can be found on the second deck of the America. Enjoy a luxurious 304 sq. ft. of living space that is equipped with full-size bathrooms and a private balcony with sliding glass doors.

A

Deckplan

These 290 sq. ft. staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, these staterooms are equipped with modern amenities, full-size bathrooms, and closet space.

Single (Private Balcony)

Deckplan

Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

Single

Deckplan

A comfortable getaway, our Single suites offer individuals a spacious room with convenient amenities. At 203 sq. ft., these staterooms have interior entrances and large opening viewing windows where the sights of the Mississippi can be enjoyed.

America Deck Plan

Deck

American Harmony

The American River Cruise revolution continues with American Harmony, the newest ship in American Cruise Lines’ highly anticipated series of contemporary riverboats. These, the first modern riverboats ever in the U.S., have introduced many pioneering innovations to America’s waters. American Harmony will feature lounges soaring 40 feet above the water with triple the glass of other riverboats for astounding views. The new riverboat will also feature the Atrium, a four-story glass-enclosed area with a large domed skylight, which will serve as the central gathering point for the entire ship.

Our new suite design will allow for unprecedented comfort while traveling, beginning with the new Grand Suites featuring 900 square feet of private space. These spacious suites include two glass walls and a wraparound private balcony. Complimentary room service during select mealtimes is available for every stateroom, but the Grand Suites offer ample space to host small cocktail parties or private dinner events.

American Harmony will continue American Cruise Lines’ decade's long tradition for innovation in river cruising. With a capacity of just 184 guests, this new ship has the modern design features and contemporary styling that today’s traveler has come to expect. Experience the American Harmony for yourself next spring on the Mississippi River. 


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Grand Suite (Private Balcony)

Deckplan

The luxurious Grand Suite measures over 900 sq. ft. and offers 270◦ of panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a wrap-around balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.

Owner's Suite (Private Balcony)

Deckplan

Each Owner’s Suite offers the finest accommodations with unsurpassed views of the passing scenery. A spectacular 575 sq. ft. of space is your private sanctuary to spread out and make yourself at home. This spacious suite features a full-size bathroom, as well as a separate bedroom and living area. Floor-to-ceiling sliding glass doors let light pour in and allow private panoramic views from every vantage point. An expansive private balcony is a perfect place to savor a calm afternoon or to enjoy breakfast as the sun rises over the riverbank.

Veranda Suite (Private Balcony)

Deckplan

With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.

AAM (Private Balcony)

Deckplan

Located on the fourth deck, these spacious staterooms feature commanding views of the passing river landscapes. At 350 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor-to-ceiling sliding glass doors with a private balcony to offer panoramic views from every angle.

AAC (Private Balcony)

Deckplan

AAC staterooms are conveniently located on the third deck and offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular views of the Mississippi River and the surrounding landscape. At 316 sq. ft., these staterooms also offer a sitting area, desk and full-size bathrooms.

AAL (Private Balcony)

Deckplan

AAL staterooms can be found on the second deck and offer a luxurious 300 sq. ft. of living space. Each room is equipped with plush seating, full-size bathroom, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. These staterooms are the epitome of comfort and relaxation.

AAR (Private Balcony

Deckplan

AAR staterooms on the main deck offer complete comfort with approximately 275 sq. ft. of living space, full-size bathrooms, and floor-to-ceiling sliding glass doors that lead out to a furnished private balcony. These staterooms also feature a large sitting area, ideal for getting together with friends.

Single (Private Balcony)

Deckplan

Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 250 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

American Harmony Deck Plan

Deck

Food & Wine Cruise


Savor exquisite regionally inspired cuisine and work one-on-one with our onboard expert to find the perfect complementary local wine. Visit amazing natural landmarks to better understand the unique topography of the region and how its diversity contributes to the wine varietals.

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Eagle Society Cruise


Explore America’s Heartland on our 11-day New Orleans to St. Louis cruise. Traveling along the legendary Mississippi River, this cruise features visits to iconic plantations and Civil War battlefields, authentic Cajun cuisine, and some of the best Jazz and Blues music you will ever hear. Visit Paducah, also known as “Quilt City,” before docking in St. Louis, home of the famous Gateway Arch. Along the way, Eagle Society members will be treated to an exclusive reception held at one of the exciting ports of call.

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The Great American Steamboat Cruise®


When the first steamboats began plying the Mississippi River in the 1800s America’s imagination was captured with notions of endless opportunity. Explorers, traders, and later the most genteel passengers were all drawn to America’s great rivers. Riverboats of every type became more numerous, faster, and grander.

Today American Cruise Lines continues this tradition with the world’s most modern paddlewheelers. This unique cruise, offered only once per year between St. Louis and New Orleans, one of the most frequented routes of old, has a special focus on these historic riverboats and the men and women who traveled on them. Historians and Riverlorians join us onboard throughout the cruise to bring the Great American Steamboat Cruise® to life.

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* Prices displayed are per person based on double occupancy.

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