Upper Mississippi River Cruise

St. Louis, MO/Alton, IL to St. Paul, MN

St. Paul, MN to Alton, IL/ St. Louis, MO

9 Days / 8 Nights

Cruise Overview

Set off on an exhilarating journey on the Upper Mississippi River, where every moment resonates with the essence of hometown Americana and the breathtaking beauty that has captivated the imaginations of our nation's most revered writers, artists, and musicians. Feel the heartbeat of the great American spirit as you follow in the footsteps of literary legend Mark Twain, who found inspiration amidst the grandeur of the river and its cascading bluffs, immortalizing them in his iconic tales. Step into the pages of history as you travel to Hannibal, the very town that shaped Twain's storytelling, where the colorful characters of Huck Finn, Tom Sawyer, and Becky Thatcher spring to life. 

From the comfort of your own private balcony, take in the unspoiled landscapes, adorned with playful wildlife. Navigate through a labyrinth of enchanting islands and get up close to the ingenious engineering of dams and locks.

As the river twists and turns, all your meals will reflect the landscape you pass. Every dish is thoughtfully curated, infused with the essence of local ingredients, ensuring each bite is a celebration of the rich culture that lines the shores of the upper Mississippi. Join us and let the energy of this remarkable journey ignite your spirit and leave you with memories to cherish for a lifetime.

Just as it was back in Mark Twain’s day, every cruise on the Upper Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary. The river has a mind of its own and our sailing schedules must adapt to it. This is part of the adventure and American Cruise Lines will always work to provide a seamless travel experience.   

Ask about our Current Savings and our Pre-Cruise Packages which include a premium hotel stay and transportation to the ship.

Upper Mississippi River Cruise Itinerary

Ships

Inaugurated 2021
Guest Capacity 180
Rooms 91
Common Areas 6
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American Melody

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Inaugurated 2015
Guest Capacity 150
Rooms 84
Common Areas 6
Ship Profile Deck 1 Highlighted Deck 2 Highlighted Deck 3 Highlighted Deck 4 Highlighted Deck 5 Highlighted

American Heritage

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Inaugurated 2022
Guest Capacity 180
Rooms 91
Common Areas 6
Ship Profile Deck 1 Highlighted Deck 2 Highlighted Deck 3 Highlighted Deck 4 Highlighted Deck 5 Highlighted

American Symphony

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Inaugurated 2023
Guest Capacity 180
Rooms 91
Common Areas 6
Ship Profile Deck 1 Highlighted Deck 2 Highlighted Deck 3 Highlighted Deck 4 Highlighted Deck 5 Highlighted

American Serenade

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Deck Plan 5

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Upcoming Cruises

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