The dramatic landscapes of the Upper Mississippi River have long inspired artists, writers, and steamboat passengers. It was here that literary great Mark Twain used the majestic river and its scenic bluffs as the settings in his most popular works. Visit his boyhood home in Hannibal, where the characters of Huck Finn, Tom Sawyer, and Becky Thatcher come to life.
Explore the beautiful gardens and historic homes of La Crosse. Get close to nature in Red Wing as you witness a variety of bald eagle nests. Enjoy a guided tour of the Black Hawk State Historic Site which celebrates the story of the Sauk and Meskwaki Indians who once called Davenport home.
Ask about our Current Savings and our Complimentary Pre-cruise Packages which include a premium hotel stay and transportation to the ship.
*The Upper Mississippi River between St. Paul and St. Louis is vulnerable to high waters which may result in itinerary changes.
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From St. Louis to St. Paul, explore historic landmarks and immerse yourself in the diverse blend of arts and entertainment. Explore destinations such as Hannibal, Davenport, and La Crosse, each offering its own fascinating story and unique culture.
Reverse itineraries available. Please contact your Cruise Specialist for your specific Day By Day agenda.
Each Mississippi itinerary comes complete with a Complimentary Pre-Cruise Package, providing you with a seamless way to board the ship and explore the local area. Arrive the day before your scheduled cruise date and American Cruise Lines will handle the rest. The package includes a premium hotel stay, where you can enjoy the city at your leisure. On the morning of the cruise, meet in the hotel lobby after breakfast and we will transport you to the ship to begin your cruise. All luggage will be brought directly from the hotel and placed in your stateroom aboard the ship.
*Pre-Cruise Package is not available for reservations made within 30 days of cruise date.
St. Louis is sure to win you over. Admire the scenic riverfront, highlighted by the majestic Gateway Arch, the largest man-made monument in the U.S. Enjoy St. Louis’ many world-class attractions, including the Art Museum, Science Center, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s most popular public gardens.
Enjoy a guided tour through two of the museum’s most popular exhibits; The 1904 World’s Fair: Looking Back at Looking Forward, an event that attracted over 200,000 visitors to the opening day and Route 66: Main Street through St. Louis, a roadway which played an important role in American History, not only in fact but in myth. Learn about the companies and tourist traps that travelers had to pass through.
Enjoy a narrated tour of downtown St. Louis, the riverfront, Citygarden, and the historic neighborhoods of Soulard and Lafayette Square. Delight in a visit to St. Louis' 1,371 acre Forest Park, known as a natural oasis in an urban environment.
*Note: This tour is only offered on cruises ending in St. Louis, MO.
Explore Hannibal, “America’s Hometown,” and experience the boyhood adventures of Mark Twain. Tom Sawyer and Huck Finn come to life in this charming Missouri town, where you can run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. The downtown area is a thriving haven for artisans filled with specialty shops unique to Hannibal.
As you arrive in Hannibal, the boyhood home of famous author Mark Twain, relive the author’s experiences that heavily influenced his writings. Visit the actual home that Mark Twain grew up in, which is surrounded by the legendary whitewashed fence of Tom Sawyer. The vivid stories told by Mark Twain come to life at this interactive museum as you explore the homes and grounds of Becky Thatcher and Huck Finn. Stop at the Interpretive Center, home to 15 original Normal Rockwell paintings; the Becky Thatcher House, the Huck Finn Home, and the Tom and Huck Statue at the foot of Cardiff Hill.
Relive the adventures of Mark Twain’s time in Hannibal during this historical trolley tour. Your experienced guide will share the history of Hannibal and take you to places of significance, including the Rockcliffe Mansion, an amazing 13,500 square foot American castle built to overlook the mighty Mississippi River. This tour will also highlight many of the exciting places which inspired Mark Twain’s famous tales.
Take in the beauty of the river as you make your way from Hannibal to Davenport. Join other guests in one of our spacious lounges or simply relax on the sun deck.
Voted one of the Most Livable Small Cities in America, Davenport is often described as a lively, active city with a hometown feel. This city features the largest agricultural exhibit in the world. Music enthusiasts will enjoy Davenport’s many music festivals, including the Mississippi Valley Blues Festival, The Mississippi Valley Fair, and the Bix Beiderbecke Memorial Jazz Festival which is dedicated to native Jazz musician Bix Beiderbecke.
Enjoy a stop at the John Deere Pavilion and Store. The company’s rich heritage is chronicled in exhibits, interactive touch screen displays, and equipment dating back nearly 175 years, including antique tractors, and giant modern combines. Continue on a narrated city tour of Davenport and learn about the Rock Island Arsenal, Davenport native Bix contribution to Jazz, Rock Island’s 1920’s “Crime Lord” John Looney, the area’s beautiful college campuses, and the city’s Native American history.
Enjoy a guided tour of the Hauberg Indian Museum. Located in the Black Hawk State Historic Site, this museum interprets the story of the Sauk and Meskwaki Indians who once called it home. During the tour, view full-size replicas of Sauk winter and summer homes, dioramas with life-size figures of the Sauk and Meskwaki Indians, and traditional artifacts, including authentic trade goods and jewelry.
A “Masterpiece on the Mississippi,” Dubuque is among the oldest settlements west of the Mississippi River. Take a ride on the Fenelon Place Elevator, the world’s shortest and steepest scenic railway or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through the whimsical downtown area, and visit the national Mississippi River Museum and Aquarium.
Step back in time and experience the elegance of Victorian-era Dubuque during a tour through the town’s many historic attractions. Learn about the architecture, families, and events that made 19th-century Dubuque such a unique treasure. Your guide will lead you through Dubuque's beautiful historic sites, including the Mathias Ham House and The Old Jail Museum.
Take an entertaining and informative journey along the mighty Mississippi at the National Mississippi River Museum and Aquarium. On this guided tour, learn about the lives of the pioneers, explorers, and artists who once lived along the Mississippi River. Get close to nature, as you make your way through six large aquariums. The museum’s interactive exhibit will give you an inside look at the Mississippi River's past, present, and future.
Step into 19th-century America in La Crosse, located on the banks of three captivating rivers. La Crosse is home to Riverside Park, where you will enjoy beautiful gardens, an outdoor performance center, and inspiring sculptures.
Take a narrated tour of this wonderful city. Discover the historic downtown with its late 19th and early 20th-century buildings, as well as the well-preserved residential neighborhoods. Gain insight into LaCrosse’s development, from the boomtown riverboat days and roaring ‘20s to the challenges and opportunities of the 21st century. Visit the Hixon House, an authentic Victorian home and designated Historic Landmark, which has retained 90% of its original furnishings.
Cruise along the scenic Mississippi River on a classic , as your tour highlights current and historical facts about the area and tests your knowledge with trivia along the way. Witness some of the most beautiful views in the Midwest, including native wildlife and steep bluffs on the river. Learn about the locking process while cruising past the Lock & Dam No. 7 in Dresbach, MN.
Nestled among the scenic bluffs of the upper Mississippi River, Red Wing's beauty has inspired artists, writers, and musicians for over 150 years, delivering a diverse blend of arts, entertainment, and activities for your pleasure. Enjoy a show at the historic Sheldon Performing Arts Theatre or observe the beauty of nature at one of Red Wing’s 38 parks.
Travel back in time, as you tour the beautiful city of Red Wing. Led by our local expert guide, view some of the most impressive Victorian homes of the period, as well as the historic St. James Hotel. Visit the Pottery Museum of Red Wing and admire the numerous vintage pieces of artisan-crafted stoneware, art pottery, dinnerware, and folk art.
Witness bald and golden eagles like never before, face-to-face! The National Eagle Center offers a unique viewing opportunity that brings visitors within a few feet of these majestic creatures with no barrier in between. This is an experience like no other and one you will never forget.
St. Paul is a thrilling river town. History buffs will enjoy a walking tour of Summit Avenue, which showcases gorgeous historic mansions built in the late 1800’s. St. Paul’s enchanting art galleries, world class museums, and entertaining stage performances will capture your imagination. End the day by visiting Mounds Park, where visitors are treated to a beautiful panoramic view of the city.
Our 8-day Upper Mississippi cruise is an enriching experience, embodying hometown Americana, abounding wildlife, and the breathtaking scenery that has inspired the country’s most legendary writers, artists, and musicians.
Some of the beautiful sites you will visit along the way:
Guest Favorites Include:
We carefully select onboard experts and performers to host enrichment programs that bring the local history, nature, and culture of the Mississippi River to life.*
*Entertainment times, days, and performers are subject to change.The Upper Mississippi and the surrounding bluffs and floodplains provide food and shelter for a variety of mammals, migrating birds, and fish. Throughout your journey you may see:
Aboard one of our modern riverboats, there are many options for spectacular viewing.
Our team of master chefs takes great pride in offering you a customized menu, featuring premium locally sourced and regionally inspired cuisine.
Sample Dinner Menu
The American River Cruise revolution continues with American Harmony, the newest ship in American Cruise Lines’ highly anticipated series of contemporary riverboats. These, the first modern riverboats ever in the U.S., have introduced many pioneering innovations to America’s waters.
American Harmony will continue American Cruise Lines’ decade's long tradition for innovation in river cruising. With a capacity of just 187 guests, this new ship has the modern design features and contemporary styling that today’s traveler has come to expect.
Featured will be lounges soaring 40 feet above the water as well as triple the glass of other riverboats, offering astounding views. The new riverboat will also feature the Atrium, a four-story glass-enclosed area with a large domed skylight, which will serve as the central gathering point for the entire ship.
Our new suite design will allow for unprecedented comfort while traveling, beginning with the new Grand Suites featuring 900 square feet of private space. These spacious suites include two glass walls and a wraparound private balcony. Complimentary room service during select mealtimes is available for every stateroom, but the Grand Suites offer ample space to host small cocktail parties or private dinner events.
Experience the American Harmony for yourself this spring on the Mississippi River.
The luxurious Grand Suite measures over 800 sq. ft. and offers 270◦ of panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a wrap-around balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.
Each Owner’s Suite offers the finest accommodations with unsurpassed views of the passing scenery. A spectacular 645 sq. ft. of space is your private sanctuary to spread out and make yourself at home. This spacious suite features a full-size bathroom, as well as a separate bedroom and living area. Floor-to-ceiling sliding glass doors let light pour in and allow private panoramic views from every vantage point. An expansive private balcony is a perfect place to savor a calm afternoon or to enjoy breakfast as the sun rises over the riverbank.
With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.
Located on the fourth deck, these spacious staterooms feature commanding views of the passing river landscapes. At 350 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor-to-ceiling sliding glass doors with a private balcony to offer panoramic views from every angle.
AAC staterooms are conveniently located on the third deck and offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular views of the Mississippi River and the surrounding landscape. At 316 sq. ft., these staterooms also offer a sitting area, desk and full-size bathrooms.
AAL staterooms can be found on the second deck and offer a luxurious 300 sq. ft. of living space. Each room is equipped with plush seating, full-size bathroom, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. These staterooms are the epitome of comfort and relaxation.
AAR staterooms on the main deck offer complete comfort with approximately 275 sq. ft. of living space. Enjoy a full-size bathroom, large picture window, and door leading out to a furnished private balcony. These staterooms also feature a large sitting area, ideal for getting together with friends.
Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 250 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.
Built in 2015, Queen of the Mississippi offers an authentic paddlewheeler experience with all the comforts of home.
Guests can enjoy large staterooms with private balconies, hotel-style bathrooms, and complimentary room service. Experience breathtaking scenery from the privacy of your stateroom as the Queen of the Mississippi makes its way down the legendary river.
At a generous up to 445 sq. ft., the Owner’s Suites of Queen of the Mississippi offer the finest accommodations with unsurpassed views of the Mississippi River. With a spacious seating area and full-size bathrooms, each suite is a private sanctuary where you can unwind after a day of exploration in the tasteful comfort of your surroundings. Each of these suites features large sliding glass doors leading out to a private balcony, where you can enjoy the ever-changing scenery. Every modern amenity is at your fingertips, along with a desk, and spacious seating area.
Located on the top deck, these spacious staterooms feature scenic views of the passing landscape. At 328 . ft., you will enjoy all of the modern comforts that are expected of a premium hotel. These staterooms also offer full-size bathrooms and a walk-out private balcony where the grandness of the Mississippi can be appreciated.
Our AAC staterooms are conveniently located on the fourth deck and at 304 sq. ft. offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape.
AAL staterooms can be found on the third deck of the Queen of the Mississippi. Enjoy a luxurious 304 . ft. of living space that is equipped with plush seating, a full-size bathroom, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery.
AAR staterooms can be found on the second deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with a full-size bathroom and a large private balcony with sliding glass doors.
These 290 sq ft staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, all are equipped with modern amenities, full-size bathrooms, and closet space.
Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.
A comfortable getaway, our Single staterooms offer individuals a spacious room with convenient amenities. At 203 . ft., all have interior entrances and large viewing windows where the sights of the Mississippi can be enjoyed.
Launched in 2016, America is one of the finest paddlewheeler ever built, introducing features never before seen on the Mississippi.
America embodies a casual ambiance and relaxed atmosphere while providing panoramic views of the passing scenery. With only 185 guests, fellow guests will quickly become new friends.
Each Owner’s Suite on America offers the finest accommodations on the Mississippi River with unsurpassed views of the passing scenery. A spectacular up to 445 sq. ft. of space is your private sanctuary to spread out and make yourself at home. Floor-to-ceiling sliding glass doors lead to an expansive private balcony offering private panoramic views throughout the room. Every modern amenity is at your fingertips, along with a spacious seating area, desk, and full-size bathroom.
Located on the top deck, these spacious staterooms feature commanding views of the passing Mississippi landscape. At 328 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor- to-ceiling sliding glass doors with a private balcony to offer panoramic views of the Mississippi from every angle. These staterooms also offer a sitting area, desk, and full-size bathrooms and are the epitome of comfort and relaxation.
AAC staterooms are conveniently located on the fourth deck and at 304 sq.ft offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape.
AAL staterooms can be found on the third deck of America. Enjoy a luxurious 304 sq. ft. of living space that is equipped with plush seating, full-size bathrooms, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery.
AAR staterooms can be found on the second deck of the America. Enjoy a luxurious 304 sq. ft. of living space that is equipped with full-size bathrooms and a private balcony complete with an outdoor seating area.
These 290 sq. ft. staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, these staterooms are equipped with modern amenities, full-size bathrooms, and closet space.
Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.
A comfortable getaway, our Single suites offer individuals a spacious room with convenient amenities. At 203 sq. ft., these staterooms have interior entrances and large opening viewing windows where the sights of the Mississippi can be enjoyed.
Few American authors are as beloved as Samuel Clemens, better known by his pen name, Mark Twain. On this special theme cruise, explore the river that served as his inspiration, complete with a true-to-life Mark Twain impersonator, and a stop in Hannibal, MO, Twain's hometown. The characters and locations of his literary classics The Adventures of Tom Sawyer and The Adventures of Huckleberry Finn come to life during our exclusive behind-the-scenes tour of the town, including a look at Huck Finn's house and the Becky Thatcher home.
With ideal temperatures and spectacular scenery, fall is the perfect time to cruise the Mississippi River. From St. Louis to St. Paul, explore idyllic American towns and witness the beauty of the landscape during peak foliage season. Enjoy customized, award-winning excursions to the area’s most captivating destinations, including a visit to the boyhood home of literary great Mark Twain.
* Prices displayed are per person based on double occupancy.
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