St. Louis - St. Paul Cruise

Eight-Days / Seven-Nights on the Upper Mississippi River
Departing from St. Louis, MO or St. Paul, MN
The dramatic landscapes of the upper Mississippi River have long inspired artists, writers and steamboat passengers. In Mark Twains’ days, changing water levels and meandering channels made navigating this stretch of river very challenging. Today, Queen of the Mississippi uses modern navigation and travels through a series of river locks which gently lower the ship more than 600 feet as we cruise from St Paul, MN to St. Louis, MO.

Gain new perspective on this magnificent living landmark with something new see to every hour of the journey. During your 8-day cruise, visit the iconic Mississippi River communities of Red Wing, La Crosse, Dubuque, Davenport, and Mark Twain’s boyhood home of Hannibal, MO. Even with the benefits of modern technology, Old Man River can be unpredictable and river conditions can change in a matter of hours. Cruise itineraries may be amended to accommodate these changes.

Request a Free Brochure or call 1-800-460-4518 for additional cruise details.
Click on Images Above to View Photo Gallery

Day 1
St. Louis, MO

St. Louis, Missouri Excursions During Mississippi River Cruise

St. Louis, known as the “Gateway to the West,” is sure to win you over. Take in the Gateway Arch Riverfront, highlighted by the majestic Gateway Arch, which is the largest manmade monument in the U.S. There’s something for everyone at St. Louis’ many world-class, free attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s top public gardens.


Day 2
Hannibal, MO

Visit Mark Twain’s Home During Mississippi River Cruise

Hannibal, “America’s Hometown,” is a place where you can rediscover adventures from Mark Twain’s era. Tom Sawyer and Huck Finn are alive in this charming Missouri town, where you can run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. The downtown area is a thriving haven for artisans filled with wonderful and special shops unique to Hannibal. No matter what you choose to do, you will find this town to be very accommodating.


Day 3
Day of River Cruising

River Cruising

Take in the beauty of the river as you make your way from Hannibal to Davenport. Join other passengers in our beautiful common areas or simply relax on the sun deck.


Day 4
Davenport, IA

Mississippi Riverboat Cruise Excursions in Davenport, IA

Voted one of the Most Livable Small Cities in America, Davenport is often described by newcomers and life-long residents alike as a lively, active city with a hometown feel. This vibrant city features the Legacy of John Deere, the largest agricultural exhibit in the world. Music enthusiasts will enjoy Davenport’s many music festivals, including the Mississippi Valley Blues Festival, The Mississippi Valley Fair, and the Bix Beiderbecke Memorial Jazz Festival, which is dedicated to native jazz musician Bix Beiderbecke.


Day 5
Dubuque, IA

Dubuque lock and dam on Queen of the Mississippi upper river cruises

A “Masterpiece on the Mississippi,” Dubuque is among the oldest settlements west of the Mississippi River. Dubuque is overflowing with things to do and see. Take a ride on the Fenelon Place Elevator, the world’s shortest and steepest scenic railway or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through a whimsical downtown area, and visit the national Mississippi River Museum and Aquarium.


Day 6
La Crosse, WI

Step into 19th century America in La Crosse, located on the banks of three captivating rivers. La Crosse is home to Riverside Park, where you’ll enjoy beautiful gardens, an outdoor performance center, and inspiring sculptures.


Day 7
Red Wing, MN

Discover Minnesota on Mississippi River Cruise

Nestled among the scenic bluffs of the upper Mississippi River, Red Wing's beauty has inspired artisans, craftspeople and artists for over 150 years. Red Wing delivers a diverse blend of arts, entertainment and activities for your pleasure. Enjoy a show at the historic Sheldon Performing Arts Theatre or observe the beauty of nature at one of Red Wing’s 38 parks.


Day 8
St. Paul, MN


St. Paul is a thrilling place to end your adventure on the Mississippi River. History buffs will enjoy a walking tour of Summit Avenue, which showcases gorgeous historic mansions built in the late 1800’s. St. Paul’s enchanting art galleries, world class museums, and entertaining stage performances will capture your imagination. End the day by visiting Mounds Park, where visitors are treated to a beautiful panoramic view of the city.



Mississippi River Cruises on Queen of the Mississippi

Beneath the gleaming woodwork and brass fixtures aboard Queen of the Mississippi is a framework of modern cruise ship technology that provides passengers with the most comfortable vacation imaginable as we cruise the Mississippi and Ohio Rivers from New Orleans to Minneapolis or Cincinnati, OH.  The Queen of the Mississippi features the most spacious staterooms in the industry and provides more space per passenger than any other river cruise ship.Click play to see more.

Date # of Nights Cruise Departure Location Ship
Aug 2, 2014 7 St. Louis - St. Paul Cruise St. Louis, MO Queen of the Mississippi
Aug 9, 2014 7 St. Louis - St. Paul Cruise St. Paul, MN Queen of the Mississippi
Sep 27, 2014 7 St. Louis - St. Paul Cruise St. Louis, MO Queen of the Mississippi
Oct 4, 2014 7 St. Louis - St. Paul Cruise St. Paul, MN Queen of the Mississippi
Aug 1, 2015 7 St. Louis - St. Paul Cruise St. Louis, MO Queen of the Mississippi
Aug 8, 2015 7 St. Louis - St. Paul Cruise St. Paul, MN Queen of the Mississippi
Aug 22, 2015 7 St. Louis - St. Paul Cruise St. Louis, MO New Mississippi Riverboat
Aug 29, 2015 7 St. Louis - St. Paul Cruise St. Paul, MN New Mississippi Riverboat
Sep 5, 2015 7 St. Louis - St. Paul Cruise St. Louis, MO New Mississippi Riverboat
Sep 26, 2015 7 St. Louis - St. Paul Cruise St. Louis, MO Queen of the Mississippi
Oct 3, 2015 7 St. Louis - St. Paul Cruise St. Paul, MN Queen of the Mississippi
Oct 10, 2015 7 St. Louis - St. Paul Cruise St. Louis, MO Queen of the Mississippi
Oct 17, 2015 7 St. Louis - St. Paul Cruise St. Paul, MN Queen of the Mississippi

QofMSR Thumbnail

Queen of the Mississippi

Queen of the Mississippi delivers an experience unlike any other riverboat. Breathing life into a once dormant market, the paddlewheeler is the first built specially for the Mississippi River in nearly 20 years and was modeled after traditional Victorian-style riverboats of the late 1800s. Queen of the Mississippi offers all of the amenities and comforts expected by today’s travelers, including large staterooms with private balconies, hotel-style bathrooms, complimentary room service, WiFi, and much more. Transporting guests back in time in the most elegant fashion, the experience aboard Queen of the Mississippi is a seamless blend of old and new. Beneath her historic décor, gleaming woodwork and brass fixtures is a framework of modern cruise ship technology that provides passengers with the most comfortable and upscale vacation imaginable on America’s Rivers.  
Rate Schedule Per Person A AAR AAL AAC Owner's Suite Single w/ Balcony Single
7 Nights $4,320 $4,975 $5,510 $5,650 $7,090 $6,330 $5,745

Rates subject to change


New Mississippi Riverboat

The new Mississippi River Paddlewheeler from American Cruise Lines is nearing completion and is scheduled to begin cruising in Spring 2015. Built specifically to cruise the Mississippi River, this new ship will provide spacious accommodations for up to 150 guests as she navigates the historic Mississippi River.
Rate Schedule Per Person A AAL AAC AAM Owner's Suite Single w/ Balcony Single
7 Nights $4,320 $5,510 $5,650 $5,855 $7,090 $6,330 $5,745

Rates subject to change




Special theme cruises offered on the St. Louis, MO to St Paul, MN cruise:

Visit Mark Twain's Hometown of Hannibal

Mark Twain Tribute Cruise


St. Louis - St. Paul - August 8, 2015 & October 3rd 2015


Delve into the life of America's most famous author - Mark Twain - on this cruise along the Mississippi River. Not only will you visit a number of fascinating ports like Burlington, Dubuque and Red Wing, you will also get a behind-the-scenes look at Hannibal, Twain's childhood hometown.

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