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American Cruise Lines explores the Mississippi River like no one else— offering 11 itineraries and 5 of the newest riverboats for unique cruises along the length of the River, including brand new American Serenade, christened in April.

American Cruise Lines announced today that it has opened the summer season operating brand new 8-Day Tennessee Rivers Cruises between Nashville and Chattanooga in Tennessee.

American Cruise Lines is pleased to announce a new cruise that visits nearly every major battlefield of the Civil War.

In a canyon at the Idaho border and alongside a bayou in Louisiana, two nearly identical cruise ships were just christened.

The newest riverboat for the Mississippi River passed sea trials this week and is on the way to New Orleans for its inaugural season exploring the country’s most iconic River.

American Cruise Lines is pleased to announce the longest-ever domestic cruise itinerary.