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Florida and Southeast United States Cruises

Cruise the Florida Coast


Florida and the southeastern region of the United States offer a unique blend of history and natural beauty. Early explorers found sanctuary in the bountiful lands of this region, and it was in these safe waters that the American ideal was born. Discover the charm of the Old South and cruise along the Intracoastal Waterway during one of our five southeast U.S. cruises. Each of these cruises offer memorable experiences you can share with like-minded travelers. Our all American crew will attend to your every need, ensuring the ultimate cruise experience.


Historic South & Golden Isles Cruise

Eight-Day / Seven-Night Cruise
Departing from Charleston, SC or Jacksonville, FL

 South and Golden Isles Cruise from Charleston or Jacksonville  

To cruise the Intracoastal Waterway is to take a trip through American history. Cruise from Charleston or Jacksonville and visit gems of the South including Beaufort, Savannah, and Hilton Head. From the American Revolution to true Dixieland culture, you will discover it all on this historic cruise.

Cruise Highlights: Charleston, Beaufort, Hilton Head, Savannah, Sapelo Island, St. Simons Island, Jekyll Island, Amelia Island, Jacksonville

Cruise from Charleston or Jacksonville




Chesapeake Bay Cruise

Eight-Day / Seven-Night Cruise
Departing from Baltimore, MD

 Cruise the Chesapeake Bay from Batlimore  

Sail the Chesapeake Bay to the Historic Triangle – Jamestown, Yorktown, and Williamsburg, and truly experience the origins of America. Continue onward to visit Annapolis and tour the U.S Naval Academy, or wander along its brick streets filled with unique shops and galleries.

Cruise Highlights: Baltimore, Williamsburg, Yorktown, Jamestown, Tangier Island, Crisfield, Cambridge, Oxford, St. Michaels,  Annapolis

Chesapeake Bay Cruise



Great Rivers of Florida Cruise

Eight-Day / Seven-Night Cruise
Departing from Jacksonville, FL

Florida Rivers Cruise   

Discover the pristine splendor and unspoiled treasures of Florida’s St. Johns and Tolomato Rivers. This eight-day cruise will bring you into the heart of Ocala National Forest, where you will encounter fascinating wildlife and lush river banks. Spend an evening anchored in Lake George, tour the Ravine Gardens State Park, and experience the quaint charm of historic St. Augustine on this memorable journey.

Cruise Highlights: Jacksonville, Palatka, Ocala National Forest, Lake George, Green Cove Springs, St. Augustine, Amelia Island

Cruise Jacksonville Florida on the Great River Cruise



East Coast Inland Passage Cruise

Fifteen-Day / Fourteen-Night Cruise
Departing from Baltimore, MD or Jacksonville, FL

 East Coast River Cruises from Baltimore or Jacksonville  

For the guest wanting the complete southern experience, this fifteen-day cruise is just for you. You will experience the best features of the east coast, explore the unique and quaint towns of Norfolk and Wilmington and take in the magnificence of historic Charleston and Savannah. End your cruise by discovering the beauty of St. Simons, Jekyll, and Amelia Islands.

Cruise Highlights: Fernandina Beach, Jekyll Island, St. Simons Island, Sapelo Island, Savannah, Hilton Head, Beaufort, Charleston, Myrtle Beach, Wilmington, Morehead City, Kitty Hawk, Norfolk, Baltimore

Cruise from Baltimore on the East Coast Inland Passage




Mid-Atlantic Inside Passage Cruise

Eight-Day / Seven-Night Cruise
Departing from Baltimore, MD or Charleston, SC

 Mid-Atlantic Inland Passage Cruise  

From the galleries and museums in historic Norfolk, to the casual, yet delightful ambiance of Myrtle Beach, this cruise offers the best of the Intracoastal Waterway. Explore the charming harbor towns of Beaufort, Kitty Hawk, and Morehead City and tour the historic riverfront of Wilmington, all while enjoying the personal touch of American Cruise Lines.

Cruise Highlights: Baltimore, Norfolk, Kitty Hawk, Beaufort, Morehead City, Wilmington, Myrtle Beach, Charleston

Cruises in South Carolina or Baltimore


Historic South Civil War Cruise

Chesapeake Bay Crabfest Cruise

  • "Thanks for a memorable trip. I love the Chesapeake more than ever."
    Veranne A., San Antonio, TX, Chesapeake Bay Cruise
  • "Everything about the cruise was terrific. The staff couldn't have done a better job of making us happy."
    Sue H., West Chester, PA, Great Rivers of Florida Cruise
  • "Traveling with American Cruise Lines is a wonderful experience with a crew of such caring, kind, and friendly people consistently working to give you an enjoyable trip."
     Geraldine B., Schaumburg, IL, Potomac and Tidewaters Cruise
  • "The cruise was wonderful; the food was great; the crew was the best I've ever seen; our stateroom was comfortable and clean...all of our needs were met cheerfully and promptly!"
    Charles T., Pearland, TX, East Coast Inland Passage Cruise

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